Objective To understand the contamination status of aflatoxin（AFT） in some commercially available foods in Kaifeng from 2015 to 2020 and evaluate the exposure level of AFT in the diet of residents and potential health risks

so as to provide scientific evidence for improving the food hygiene standards in Kaifeng. Methods A total of 738 samples of cereal products

vegetable oils

nuts and seeds

condiments

dairy products

wine

tea

beans

and soy products were randomly collected from supermarkets and farmers’ markets in 9 counties and districts of Kaifeng City. Aflatoxin M

1

（AFM

1

） in dairy products was detected by liquid chromatography-fluorescence detection. Aflatoxin B

1

（AFB

1

）

aflatoxin B

2

（AFB

2

）

aflatoxin G

1

（AFG

1

）

and aflatoxin G

2

（AFG

2

） in other samples were detected by immunoaffinity column purification-high performance liquid chromatography. The detection results were evaluated. The food frequency method was used to collect the above food consumption of Kaifeng residents. The simple distribution assessment and margin of exposure（MOE） method were used to calculate the dietary AFB

1

exposure level and carcinogenic risk. Results AFT was detected in 267 of 738 samples

with a detection rate and the total excess rate of 36.2% and 5.0%

respectively. The highest excess rate of AFT was detected in peanuts（15.3%）. The detection rate of AFB

1

was the highest among the four AFTs（AFB

1

AFB

2

AFG

1

AFG

2

） of 25.7%

and the highest detection levels of AFT and AFB

1

were 43.700 ug/kg and 36.400 ug/kg in peanuts

respectively. The total dietary exposure to AFB

1

in Kaifeng residents was 12.07 ng/kg BW

and cereals and their products

edible vegetable oils

nuts

condiments

soy products

and alcoholic beverages contributed 9.36%

22.29%

58.32%

6.46%

2.82%

and 0.99% to AFB

1

dietary exposure

respectively. Residents’ risk of liver cancer through consumption of AFB

1

-contaminated food was 0.025 per 100 000 persons for cereals and their products

0.059 per 100 000 persons for vegetable oils

0.154 per 100 000 persons for nuts

0.017 per 100 000 persons for seasonings

0.007 per 100 000 persons for soy products

and 0.003 per 100 000 persons for alcoholic beverages. MOE values from low to high were: nuts

edible vegetable oils

cereals and their products

condiments

soy products

and alcoholic beverages. Conclusion AFT contamination was observed in commercial food in Kaifeng City. Nuts and vegetable oils are important foods that cannot be ignored in controlling AFT exposure level and carcinogenic risk in the diet of Kaifeng residents. Supervision and publicity should be strengthened to guide the healthy diet of the public.