Objective To investigate the effects of threshold pressure-loaded respiratory muscle training on pulmonary function

exercise tolerance and respiratory muscle strength in patients with chronic obstructive pulmonary disease（COPD）. Methods A total of 91 patients with COPD admitted to a hospital in Luoyang from October 2018 to October 2020 were selected as subjects

who were assigned to a control group（n=45） and an observation group（n=46） using the random number table method. Patients in the control group received conventional respiratory muscle training

and patients in the observation group threshold pressure-loaded respiratory muscle training. Patients in both groups received continuous intervention for 2 months. Pulmonary function

exercise endurance and respiratory muscle strength were compared between the two groups before and after the intervention. Results After the intervention

Forced Expiratory Volume In 1s（FEV

1

） and Forced Vital Capacity（FVC） in both groups were higher than those before the intervention

with the observation group higher than the control group

and the difference was statistically significant（P

<

0.05）.The 6 Minutes Walk Test（6MWT） in both groups was longer than those before the intervention

with the observation group longer than the control group

and the difference was statistically significant（P

<

0.05）.The resting heart rate in both groups was lower than that before the intervention

with the observation group lower than the control group

and the difference was statistically significant（P

<

0.05）.The Maximum Expiratory Pressure（MEP） and Maximum Inspiratory Pressure（MIP） in both groups were higher than those before the intervention

with the observation group higher than the control group

and the difference was statistically significant（P

<

0.05）.Conclusion Threshold pressure loading respiratory muscle training can effectively improve pulmonary function

exercise endurance and respiratory muscle strength level in patients with COPD

demonstrating marked effects. These advantages justify a wider application of this technique clinically.