Objective To investigate the effect of comprehensive nursing on surgery-related indicators and pain degree in the treatment of acute appendicitis with transumbilical lapatraroendoscopic single-site surgery. Methods One hundred and twenty patients with acute appendicitis treated by transumbilical lapatraroendoscopic single-site surgery in a hospital in Nanyang City from April 2019 to April 2021 were selected as participants and assigned to a control group and an observation group using the random number table method

with 60 patients in each group. The patients in the control group received conventional nursing during the perioperative period

while the patients in the observation group received comprehensive nursing during the perioperative period. The perioperative related indicators

postoperative quality of life

postoperative pain

satisfaction and complications were compared between the two groups. Results The operation time

anal exhaust time and length of stay of the observation group were shorter than those of the control group

and the differences were statistically significant（P<0.05）. The pain score of the observation group was lower than that of the control group

and the satisfaction score was higher than that of the control group

both with statistically significant difference（P<0.05）. The incidence of complications in the observation group was 3.33%

which was lower than that in the control group（20.00%）

and the difference was statistically significant（P<0.05）. Conclusion The use of comprehensive nursing in treating acute appendicitis with transumbilical lapatraroendoscopic single-site surgery can help shorten the operation time

anal exhaust time and length of stay

reduce the pain triggered by the operation

and improve the quality of life and satisfaction of patients.