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1. 伊川县人民医院妇产科
2. 河南科技大学第一附属医院产科
3. 洛阳市中心医院妇科
纸质出版日期:2022,
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武辉, 陈素娟, 刘恒, 等. 地诺前列酮与宫颈扩张球囊在足月初产妇引产中的应用效果比较[J]. 保健医学研究与实践, 2022,19(5):62-65.
Wu Hui, Chen Sujuan, Liu Heng, et al. Comparison of the effects of PEG2 and cervical ripening balloon in induction of labor in full-term primigravida[J]. Health Medicine Research and Practice, 2022,19(5):62-65.
目的 比较分析地诺前列酮与宫颈扩张球囊在足月初产妇引产中的应用效果。方法 本研究选取2018年12月—2020年12月河南省某医院收治的72例足月妊娠引产产妇为研究对象。采用随机数字表法将患者分为A组(n=37)与B组(n=35)。A组患者接受宫颈扩张球囊引产
B组患者接受地诺前列酮引产。比较2组新生儿出生1、5、10 min时阿普加(Apgar)评分及新生儿出生体质量;比较2组患者产后出血量、产后Bishop评分、总产程时长、分娩方式与不良事件发生情况。结果 2组新生儿出生1、5、10 min时Apgar评分比较
差异无统计学意义(P>0.05)。2组新生儿出生5、10 min时Apgar评分均高于出生1 min时
差异均有统计学意义(P<0.05)。2组新生儿出生时体质量比较
差异无统计学意义(P>0.05)。2组患者Bishop评分比较
差异无统计学意义(P>0.05)。B组患者产后出血量多于A组
总产程时长长于A组
差异均有统计学意义(P<0.05)。2组患者不良事件发生率比较
差异无统计学意义(P>0.05)。B组患者剖宫产率高于A组
差异有统计学意义(P<0.05)。结论 在足月妊娠引产产妇中使用地诺前列酮与宫颈扩张球囊对新生儿均具有较高安全性
且2种方式的引产效果均较为理想
但使用宫颈扩张球囊引产的产妇出血风险及剖宫产率更低
临床应根据产妇实际情况酌情选择引产方式。
Objective To compare and analyze the effects of dinoprostone(PGE2) and cervical ripening balloon in the induction of labor in full-term primiparous women.Methods Seventy-two cases of full-term pregnancy induction admitted to a hospital in Henan Province from December 2018 to December 2020 were selected for this study.The patients were divided into group A(n=37) and group B(n=35) using a random number table.Patients in group A received cervical ripening balloon induction of labor and patients in group B received PGE2 induction of labor.The Apgar scores at 1
5 and 10 min of birth and the birth mass of the neonates in the two groups were compared;the amount of postpartum hemorrhage
postpartum Bishop score
total length of labor
delivery method and adverse events in the two groups were compared.Results There was no statistically significant difference(P>0.05) between the Apgar scores of neonates in the 2 groups at 1
5 and 10 min of birth
and the Apgar scores of neonates in the 2 groups at 5 and 10 min of birth were higher than those at 1 min of birth
with statistically significant differences(P<0.05).There was no statistically significant difference in the body mass of the neonates between the 2 groups(P>0.05)
and there was no statistically significant difference in Bishop score between the 2 groups(P>0.05).Patients in group B had more postpartum bleeding and longer total labor length than group A
with statistically significant differences(P<0.05).There was no statistically significant difference in the incidence of adverse events between the 2 groups(P>0.05).Conclusion The use of PGE2 and cervical ripening balloon in the induction of labor in full-term pregnancy has a higher safety for the neonates
and the induction results of both methods are relatively satisfactory
but the risk of hemorrhage and the cesarean section rate are lower in the induction of labor with cervical ripening balloon
so the clinical choice of induction method should be made according to the actual situation of the mother.
足月妊娠产妇引产宫颈扩张球囊宫颈成熟地诺前列酮
Full-term pregnancyInduction of laborCervical ripening balloonCervical ripeningDinoprostone
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