Objective To study the characteristics of body fat distribution and the correlation between visceral and subcutaneous fat content and related metabolic indexes in diabetic ketosis patients. Methods Forty-six patients with diabetic ketosis admitted to a hospital in Chengdu from February 2007 to May 2018 were selected for the study

and their general clinical data

including gender

age

body mass index（BMI）

blood pressure and lipids（TG

TC

LDL-C）

random blood glucose

glycosylated hemoglobin（HbA1c）

uric acid

and β-hydroxybutyric acid levels

were collected. Visceral fat area（VFA） and subcutaneous fat area（SFA） were calculated for all patients using abdominal CT data. Pearson correlation analysis was used to analyze the correlation between VFA and SFA and HbA1c

blood lipids

uric acid

and BMI. Results The general data of 46 diabetic ketosis patients are shown in Table 1

including 13 patients with type 1 diabetes

16 patients with type 2 diabetes

and 17 patients with undetermined diabetes. The mean VFA of patients was 97.92±59.10 cm~2 and the mean SFA was 144.50±78.26 cm~2. Patients’ VFA and SFA were negatively correlated with HDL-C（r=-0.517

P<0.001; r=-0.392

P=0.007） and positively correlated with BMI（r=0.823

P<0.001; r=0.734

P<0.001）. The VFA and SFA of patients were not correlated with their random blood glucose

systolic blood pressure

diastolic blood pressure

HbA1c

TG

TC

LDL-C

or uric acid（P>0.05）. Conclusion VFA and SFA were associated with decreased HDL-C level and increased BMI in diabetic ketosis patients

suggesting that fat accumulation in the body may be a risk factor for metabolic syndrome and cardiovascular events.