肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值

王国庆; 冯田; 胡爱侠

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肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值

临床医学 | 更新时间：2022-11-04

- 肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值
- The value of lung biopsy combined with cytological rapid on-site evaluation in the diagnosis of lung shadowing
- 保健医学研究与实践 2022年19卷第4期页码：60-62
- 作者机构：
  
  1. 焦作市人民医院病理科
  2. 河南省人民医院病理科
- 作者简介：
- 基金信息：
  
  河南省重大科研专项项目(161100311400)
- DOI：
  中图分类号： R734.2
- 纸质出版日期：2022，
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王国庆, 冯田, 胡爱侠. 肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值[J]. 保健医学研究与实践, 2022,19(4):60-62.

Wang Guoqing, Feng Tian, Hu Aixia. The value of lung biopsy combined with cytological rapid on-site evaluation in the diagnosis of lung shadowing[J]. Health Medicine Research and Practice, 2022,19(4):60-62.
王国庆, 冯田, 胡爱侠. 肺活检技术联合快速现场细胞学评价在肺部阴影诊断中的价值[J]. 保健医学研究与实践, 2022,19(4):60-62. DOI：

Wang Guoqing, Feng Tian, Hu Aixia. The value of lung biopsy combined with cytological rapid on-site evaluation in the diagnosis of lung shadowing[J]. Health Medicine Research and Practice, 2022,19(4):60-62. DOI：

摘要

目的分析肺活检技术联合快速现场细胞学评价（C-ROSE）在肺部阴影诊断中的价值。方法选取2019年1月—2021年3月焦作市某医院收治的168例肺部阴影患者为研究对象。所有患者均行超声引导下经皮穿刺肺活检

并根据是否采用C-ROSE将其分为C-ROSE组（84例）和常规细胞学检查组（84例）

以组织学病理结果为金标准

比较2组患者肺部阴影诊断结果以及穿刺次数、手术操作时间、二次穿刺活检阳性率、穿刺后并发症发生率。结果组织学病理结果显示

C-ROSE组患者中恶性肿瘤患者70例

良性病变患者14例;常规细胞学检查组患者中恶性肿瘤患者68例

良性病变患者16例。C-ROSE组患者诊断肺部阴影的灵敏度为94.29%、特异度为78.57%、准确率为91.67%

Kappa值为0.708

与金标准的一致性较高。常规细胞学检查组患者诊断肺部阴影的灵敏度为79.41%、特异度为75.00%、准确率为78.57%

Kappa值为0.439

与金标准的一致性中等。C-ROSE组患者的穿刺次数、二次穿刺活检阳性率均低于常规细胞学检查组

差异均有统计学意义（P

0.05）;C-ROSE组患者的手术操作时间长于常规细胞学检查组

差异有统计学意义（P

0.05）。C-ROSE组患者穿刺后并发症发生率为4.76%

低于常规细胞学检查组的14.29%

差异有统计学意义（χ

4.421

P=0.035）。结论肺活检技术联合C-ROSE可提高肺部阴影患者的诊断效能

降低穿刺次数、二次穿刺活检阳性率及穿刺后并发症发生率。

Abstract

Objective To analyze the value of lung biopsy combined with cytological rapid on-site evaluation（C-ROSE） in the diagnosis of lung shadowing. Methods One hundred and sixty-eight patients with lung shadowing admitted to a hospital in Jiaozuo from January 2019 to March 2021 were selected for the study. All patients underwent ultrasound-guided percutaneous puncture lung biopsy

and they were divided into the C-ROSE group（84 cases） and the conventional cytology group（84 cases） according to whether C-ROSE was used

and the histological pathology results were used as the gold standard to compare the diagnostic results of lung shadowing as well as the number of punctures

surgical operation time

secondary puncture biopsy rate

and complication rate in the 2 groups. Results The results of histological pathology showed that there were 70 patients with malignant tumors and 14 patients with benign lesions in the C-ROSE group

and 68 patients with malignant tumors and 16 patients with benign lesions in the conventional cytology group. The sensitivity of patients in the C-ROSE group for the diagnosis of lung shadowing was 94.29%

the specificity was 78.57%

the accuracy was 91.67%

and the Kappa value was 0.708

with high agreement with the gold standard. The sensitivity of patients in the conventional cytology group for the diagnosis of lung shadowing was 79.41%

the specificity was 75.00%

the accuracy was 78.57%

and the Kappa value was 0.439

which were in moderate agreement with the gold standard. The number of punctures and the rate of secondary puncture biopsies in the C-ROSE group were lower than those in the conventional cytology group

and the differences were statistically significant（P

0.05）; the operation time in the C-ROSE group was longer than that in the conventional cytology group

and the difference was statistically significant（P

0.05）. The complication rate of patients in C-ROSE group during treatment was 4.76%

which was lower than that of 14.29% in conventional cytology group

and the difference was statistically significant（χ

4.421

P=0.035）. Conclusion Lung biopsy combined with C-ROSE can improve the diagnostic efficacy and reduce the number of punctures

secondary puncture biopsy rate and complication rate in patients with lung shadowing.

关键词

肺活检技术快速现场细胞学评价肺部阴影

Keywords

Lung biopsy techniqueCytological rapid on-site evaluationLung shadowing

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