Objective To explore the self-management status of HIV/AIDS patients and related influencing factors.Methods A total of 150 patients with HIV/AIDS attending a hospital in Kaifeng from April 2018 to March 2019 were selected as study subjects using convenience sampling method

and a questionnaire survey was conducted using the HIV/AIDS self-management scale.Results The results of univariate analysis showed that there were statistically significant differences（P<0.05） in the scores of HIV/AIDS self-management scale among the study subjects with different physical status

education level

disease duration and antiviral treatment status

and disease awareness.The highest score among the three dimensions of the HIV/AIDS self-management scale was the dimension of long-term self-management（2.23±0.67）

followed by the daily health management dimension（1.93±0.41）

and finally the social support dimension of self-management（1.86±0.45）.Linear regression results showed that education level

disease duration and knowledge of the disease were influential factors in the self-management scale scores of HIV/AIDS patients in this study（P<0.05）.Conclusion Education level

disease duration and disease awareness are the main factors affecting the self-management ability of HIV/AIDS patients

and health education for HIV/AIDS patients should be strengthened to improve their self-management ability

which is conducive to improving the treatment effect and life quality.