Objective To explore the prevention effect of care bundle intervention on delirium in patients with dementia.Methods One hundred and twenty patients with Alzheimer’s disease accompanied by delirium who were treated in a hospital in Shangqiu city from January 2019 to June 2021 were selected as study subjects and divided into a control group and an observation group according to the random number table method

with 60 cases each.The patients in the control group were given conventional nursing interventions

while the observation group was given care bundle interventions

and the patients in both groups were continuously nursed for 6 months.The occurrence of delirium and the duration of delirium in the two groups were compared

and the quality of life of the patients in the two groups before and after care was compared.Results The incidence of delirium in the control group was 16.67%（10/60）

which was higher than that in the observation group（8.33%

5/60）

and the difference was statistically significant（χ~2=5.485

P=0.023）;the duration of delirium in the observation group was（2.18±1.36）min

which was significantly shorter than that in the control group [（5.24±2.58）min]

and the difference was statistically significant（t=8.127

P<0.001）.Before care

there was no statistically significant difference in the scores of somatic function

social communicative ability

physical activity

and psycho-emotional scores between the 2 groups of patients（P>0.05）.After nursing care

the scores of somatic function

social communicative ability

organism activity ability

and psycho-emotional scores of patients in the 2 groups were higher than those before nursing care and higher in the observation group than in the control group

with statistically significant differences（P<0.05）.Conclusion Care bundle intervention can reduce the incidence of delirium

shorten the duration of delirium and improve the quality of life of patients with dementia

and deserves clinical promotion.