Objective To investigate the clinical efficacy of Qiang pepper fumigation powder in the treatment of osteoarthritis（OA） of the knee.Methods Seventy-three cases of OA patients admitted to a hospital in Nanchong from December 2020 to March 2021 were selected as the study subjects.The patients were divided into the control group（n=37） and the study group（n=36） using a random number table.Patients in the control group were treated with oral meloxicam tablets

and patients in the study group were treated with Qiang pepper fumigation powder.The clinical effect at were 6 of treatment was compared betueen the two groups.Results The total clinical treatment efficiency of patients in the study group was 94.44%

which was higher than that of the control group（67.57%）

and the difference was statistically significant（P<0.05）.Conclusion Qiang pepper fumigation powder can improve the therapeutic effect of OA and promote the recovery of patients.Therefore

it is worth wider clinical application.