基于治疗药物监测的1例抗结核药物性肝损伤患儿治疗方案调整

鲁虹; 史群志; 吴戈; 刘芳群

您当前的位置：

首页 >

文章列表页 >

基于治疗药物监测的1例抗结核药物性肝损伤患儿治疗方案调整

本期目录 | 更新时间：2022-11-04

- 基于治疗药物监测的1例抗结核药物性肝损伤患儿治疗方案调整
- Adjustment of Treatment Regimen for a Child with Anti-Tuberculosis Drugs-Induced Liver Injury Based on Therapeutic Drug Monitoring
- 儿科药学杂志 2022年28卷第8期页码：5-9
- 作者机构：
  
  南华大学附属长沙中心医院,长沙,410004
- 作者简介：
- 基金信息：
  
  湖南长沙市2019 年第二批重点研发、平台和人才科技计划项目,编号kq1907019
- DOI：
  中图分类号：
- 纸质出版日期：2022，
扫描看全文
鲁虹, 史群志, 吴戈, 等. 基于治疗药物监测的1例抗结核药物性肝损伤患儿治疗方案调整[J]. 儿科药学杂志, 2022,28(8):5-9.

Lu Hong, Shi Qunzhi, Wu Ge, et al. Adjustment of Treatment Regimen for a Child with Anti-Tuberculosis Drugs-Induced Liver Injury Based on Therapeutic Drug Monitoring[J]. 2022,28(8):5-9.
鲁虹, 史群志, 吴戈, 等. 基于治疗药物监测的1例抗结核药物性肝损伤患儿治疗方案调整[J]. 儿科药学杂志, 2022,28(8):5-9. DOI：

Lu Hong, Shi Qunzhi, Wu Ge, et al. Adjustment of Treatment Regimen for a Child with Anti-Tuberculosis Drugs-Induced Liver Injury Based on Therapeutic Drug Monitoring[J]. 2022,28(8):5-9. DOI：

摘要

目的：通过观察1例13岁儿童患者应用抗结核药物导致药物性肝损伤（DILI）的治疗过程，探讨临床药师在疾病预防和治疗中的作用。方法：临床药师参与1例儿童应用抗结核药物致DILI的治疗过程，根据抗结核药物治疗药物监测（TDM）结果提出用药建议，调整儿童抗结核药物的治疗方案。结果：临床医师部分采纳药师建议，调整用药方案，患儿病情和肝损伤明显改善。结论：TDM是临床药师参与药物治疗的有效技术手段，可保障疾病治疗过程中的用药安全有效。

Abstract

Objective: To probe into the role of clinical pharmacists in disease prevention and treatment through the treatment process of a 13-year-old child with drug-induced liver injury (DILI) induced by anti-tuberculous drugs. Methods: The clinical pharmacists participated into the treatment process of a child with DILI induced by anti-tuberculous drugs

put forward suggestions according to the results of therapeutic drug monitoring (TDM) on anti-tuberculous drugs

and adjusted the treatment regimen of anti-tuberculosis drugs in children. Results: The clinicians partly adopted the suggestions by clinical pharmacists and adjusted the medication regimen

the disease conditions and liver function of the children were significantly improved. Conclusion: TDM is an effective technical means for clinical pharmacists to participate into drug treatment

which can ensure the safety of drugs in disease treatment

关键词

药物性肝损伤抗结核药物治疗药物监测

Keywords

rug-induced liver injuryanti-tuberculosis drugstherapeutic drug monitoring

references

查看原文

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

癫痫患儿丙戊酸剂量校正血药浓度的非遗传变异影响因素分析

104 例新生儿地高辛的应用与治疗药物监测

伏立康唑血药浓度监测在儿童血液病的临床应用

临床药师参与诊治1例儿童药物性肝损伤的实践体会