Objective：To explore the clinical characteristics of coronavirus disease 2019（COVID-19）. Methods：The clinical data of 24 patients with COVID-19 were analyzed retrospectively. Results：Among the 24 patients，14 were male and 10 were female，and 22 had a history of living in Wuhan，accounting for 91.7%；fever and cough were the main clinical manifestations，accompanied by in－fluenza-like symptoms such as headache，fatigue，and muscle soreness. All patients were cured or improved by comprehensive treatment including supportive treatment，antiviral，oxygen therapy and glucocorticoid. The time of nucleic acid turning negative was （20.41±7.12） days. Conclusion：Combined with the epidemiological history，fever，CT pneumonia manifestation and the normal or decrease of leukocyte and lymphocyte count can be used as the clinical basis for diagnosing of the disease. The decrease of T lymphocyte count has a certain correlation with patients’ condition and prognosis. The cure rate is high，but the patient has a long duration of viral shedding，therefore，the isolation time must be prolonged.