Since from December 2019，coronavirus disease 2019（COVID-19） has caused tens of thousands of infections，and all areas have launched the first-level public health emergency response. In the epidemic situation，pediatric clinical nutrition not only faces unprecedented high risks of the infection prevention and control links，such as breast feeding，nutrient solution preparation，and per－sonnel-and-environmental management，but also needs to design individualized nutrition treatment plan for infected children urgently. In this paper，main problems of pediatric clinical nutrition under the epidemic situation are put forward and corresponding solutions are discussed.