Xiong Xiaoqin, Feng Wei, Li Xiaoyu, et al. Analysis of risk factors influencing the prognosis of full-term and preterm infants with necrotizing enterocolitis[J]. Journal of Chongqing Medical University, 2020,45(9):1350.
Xiong Xiaoqin, Feng Wei, Li Xiaoyu, et al. Analysis of risk factors influencing the prognosis of full-term and preterm infants with necrotizing enterocolitis[J]. Journal of Chongqing Medical University, 2020,45(9):1350.DOI:
Objective:To investigate risk factors influencing prognosis of neonatal necrotizing enterocolitis(NEC) in full-term infants and preterm infants. Methods:The clinical data of 287 NEC patients(BELL stage≥Ⅱ) were retrospectively analyzed and divided into full-term group(n=128) and the preterm group(n=159) according to gestational age. and then use The univariate and multivariate logistic regression analysis was used to summarize risk factors influencing NEC prognosis in full-term and preterm infants. Results:NEC analysis in the full-term group showed that Ⅲ-stage NEC(OR=63.052,95%CI=2.373-1674.987,P=0.013) and complication of respiratory failure(OR=85.917,95%CI=3.005-2456.151,P=0.009) were independent risk factors for prognosis;probiotics(OR=0.036,95%CI=0.002-0.809,P=0.036) was protective factor. NEC analysis in the preterm group showed that sepsis(OR=5.669,95%CI=1.829-17.569,P=0.003) was independent risk factor influencing prognosis,and probiotics(OR=0.172,95%CI=0.054-0.547,P=0.003) was protective factor. Conclusion:There are some differences in risk factors of NEC prognosis in preterm and full-term infants,and clinical treatment should be individualized to improve prognosis.