Objective：To compare the accuracy of two Montreal cognitive assessment five-minute protocols in stroke patients. Methods：A prospective observational study enrolled stroke patients and healthy subjects from the Department of Rehabilitation Medicine of The Second Affiliated Hospital of Chongqing Medical University. National institute for neurological disorders and stroke-Canadian stroke network（NINDS-CSN），Montreal cognitive assessment 5-minute protocol（Hong Kong version），Montreal cognitive assessment（MoCA）and neurobehavioral cognitive status examination（NCSE） were administered to each participant. Results：A total of 29 patients with stroke and 20 healthy controls were enrolled in this study. The results of the two Montreal cognitive assessment five-minute protocols were consistent with the results of the MoCA with correlation coefficients of 0.918 6（P<0.001） and 0.918 1（P<0.001），respectively. NINDS-CSN is better than the Montreal cognitive assessment 5-minute protocol（AUC=0.934；95%CI=0.825-0.985）. Conclusion：The validity of the two Montreal cognitive assessment five-minute protocols is consistent with that of MoCA. The NINDS-CNS five-minute assessment is more suitable for clinical community promotion and application than the MoCA 5-minute protocol.