Gastric cancer is a gastrointestinal malignancy with a high incidence rate

and it greatly threatens the health and survival of human due to advanced stage at the time of identification and poor prognosis. Circular RNA（circRNA）is a new type of regulatory RNA with a closed covalent ring structure

which brings significant enzyme resistance

and it regulates gene expression in various eukaryotes. Studies have shown that the biological function and abnormal expression of circRNA can affect the development and progression of tumors

and thus it has a potential value in the diagnosis and prognostic evaluation of tumor. Therefore

it is of great significance to explore the role of circRNA in gastric cancer and its possibility as a biomarker

so as to provide new ideas for the diagnosis and prognosis of gastric cancer. This article summarizes the significance of circRNA in the diagnosis and prognosis of gastric cancer.