Objective: To investigate the CT findings of anomalous systemic arterial supply to the normal lung

and to improve the understanding of the imaging findings of this disease and reduce misdiagnosis and missed diagnosis. Methods: A retrospective analysis was performed for the imaging data of 2 patients with anomalous systemic arterial supply to the normal lung in our center and 105 patients reported in literature. Results: The anomalous systemic artery was observed in all patients and originated from the thoracic aorta in 104 patients

the celiac axis in 2 patients

and the descending thoracic aorta and the celiac axis in 1 patient. Among these patients

49 had normal density and 38 had ground-glass density of lung tissue in the affected lung segment

with consolidation observed in a few patients. Of all patients

3 had reduced pulmonary artery

1 had uncertain pulmonary arterial supply in the affected lung segment

and 103 had absence of the pulmonary artery. All patients had normal bronchial tree and pulmonary vein reflux in the affected lung segment. Conclusion: Typical CT manifestations of anomalous systemic arterial supply to the normal lung include lung tissue with normal distribution of bronchus and pulmonary venous reflux supplied by an anomalous systemic artery

mostly normal or ground-glass density in the affected lung segment

and absent or reduced artery of corresponding pulmonary lobe/segment

and this disease can be diagnosed by contrast-enhanced computed tomography.