Objective:To investigate the prescription rules of traditional Chinese medicine（TCM） therapy fornonalcoholic fatty liver disease（NAFLD）. Methods:The articles on NAFLD published from January 2010 to April2020 were collected and included based on related criteria

and a statistical analysis was performed for the articlesthat met inclusion criteria. Results:There were 239 eligible articles on TCM therapy for NAFLD

involving 239 pre-scriptions and 163 drugs

among which those not recorded in Science of Chinese Materia Medica and Chinese HerbalMedicine were excluded. The total frequency of drugs was 2 554. A total of 12 drugs had a cumulative frequency of >50 %

i.e.

Hawthorn fruit

Alisma orientalis

Salvia miltiorrhiza

Bupleurum chinense

Poria cocos

Atractylodesmacrocephala

Radix glycyrrhizae

Curcuma aromatica

Tangerine peel

Cassia seed

Pinellia ternate

and Artemisiacapillaris. As for nature

flavor

and meridian tropism

most drugs were slightly cold and bitter and were attributed tothe liver meridian.As for function

most drugs were deficiency-tonifying herbs

diuresis-inducing and damp-ness-draining herbs

and blood-activating and stasis-resolving herbs.Conclusion: Liver-soothing andspleen-strengthening

diuresis-inducing and dampness-draining

and blood-activating and stasis-resolving thera-pies are mainly used for the treatment of NAFLD

which are supplemented by the phlegm-eliminating

diges-tion-promoting

heat-clearing

and Qi-regulating therapies.