Objective:To investigate the expression of the long non-coding RNA（lncRNA） ABHD11-AS1 in cervical cancer and its association with diagnosis and prognosis. Methods:Quantitative real-time PCR was used to measure the expression level of lncRNA ABHD11-AS1 in blood samples of 50 patients with cervical cancer and the subjects in the control group

and the association of the relative expression level of lncRNA ABHD11-AS1 with the diagnosis

clinicopathological features

and prognosis of cervical cancer patients was analyzed. Results:There was a significant difference in the relative expression level of lncRNA ABHD11-AS1 in blood samples between the patients with cervical cancer and the control group（1.80 ± 0.11 vs 1.17 ± 0.08

P < 0.05）. The expression level of lncRNA ABHD11-AS1 was associated with lymph node metastasis

lymphatic vessel invasion

tumor size

and FIGO stage in patients with cervical cancer（P < 0.05）

while it was not associated with patients’ age and menopause status. The receiver operating characteristic curve analysis showed that lncRNA ABHD11-AS1 had certain diagnostic significance as a marker for cervical cancer. Compared with the low lncRNA ABHD11-AS1 expression group

the high lncRNA ABHD11-AS1 expression group had a significantly shorter median OS（P < 0.05）. Conclusion:The expression of lncRNA ABHD11-AS1 is upregulated in cervical cancer

and lncRNA ABHD11-AS1 can be used as a potential molecular marker for diagnosis and prognosis.