Objective To investigate the clinical efficacy of respiratory training combined with budesonide formoterol in the treatment of chronic obstructive pulmonary disease（COPD） in the stable stage. Methods Ninety patients with stable COPD admitted to a hospital in Liaoning Province from January 2017 to December 2019 were selected and divided into a control group and an experimental group with 45 patients in each group using a randomized numerical table. Patients in the control group were treated for 16 weeks with budesonide formoterol inhaler

and patients in the experimental group were treated for 16 weeks with respiratory training on the basis of the control group. Pulmonary functions Parameters [forced vital capacity（FVC）

Forced expiratory volume in 1 second（FEV1）

FEV1/FVC]

serum biochemical parameters [interleukin（IL）-17 A

C-reactive protein（CRP）

IL-6]

blood gas analysis parameters [arterial partial pressure of oxygen（Pa O

2

）

arterial partial pressure of carbon dioxide（Pa CO

2

）]

quality of life [St. George’s Respiratory Questionnaire（SGRQ） score]

and clinical efficacy were compared between the two groups before and after treatment. Results The total effective rate of treatment in the experimental group was 95.56%

which was higher than the 80.00% in the control group

and the difference was statistically significant（P

<

0.05）. Before treatment

the levels of FVC

FEV1 and FEV1/FVC of the two groups were compared

and the difference was not statistically significant（P

>

0.05）. After treatment

the levels of FVC

FEV1 and FEV1/FVC of both groups were significantly higher than before treatment

and those in the experimental group were higher than the control group; the differences were all statistically significant（P

<

0.05）. Before the treatment

the Pa CO

2

and Pa O

2

levels of the 2 groups were compared

and the differences were not statistically significant（P

>

0.05）. After the treatment

the Pa CO

2

level of both groups was lower than before the treatment

the Pa O

2

level was higher than before the treatment

the Pa CO

2

level of the experimental group was lower than the control group

and the Pa O

2

level was higher than the control group; the differences were all statistically significant（P

<

0.05）. Before treatment

the serum IL-17 A

IL-6 and CRP levels of the two groups were compared

and the differences were not statistically significant（P

>

0.05）. After treatment

the serum IL-17 A

IL-6 and CRP levels of both groups were lower than before treatment

and those in the experimental group were lower than those in the control group; the differences were all statistically significant（P

<

0.05）. Before treatment

the SGRQ scores of the two groups were compared

and the differences were not statistically significant（P

>

0.05）. After treatment

the scores in pulmonary symptoms

mobility

and disease-influencing dimensions of both groups were lower than those before treatment

and those in the experimental group were lower than those in the control group; the differences were all statistically significant（P

<

0.05）. Conclusion Respiratory training combined with budesonide formoterol helps to improve the inflammatory state and lung function of patients with stable COPD and improve their quality of life

with significant clinical efficacy

and thus is worth promoting.