Objective To explore the mental health status and post-traumatic stress disorder of medical staff in fighting against COVID-19

find out all kinds of psychological problems as early as possible

and provide scientific basis for later intervention. Methods By convenience sampling

306 hospital staffs against COVID-19 from 8 fixed-point treatment hospitals were assessed with the general information questionnaire

PCL-C and GHQ-12 by Internet survey. Analysis was conducted by SPSS 22.0. Results The average score of PCL-C was 32.34±8.32 and 87 persons were positive to PTSD（28.43%）. The average score of GHQ-12 was 24.13±7.08 and 85 persons were positive to GHQ-12（27.78%）. Correlation analysis showed that mental health status was positively correlated with post-traumatic stress reaction（r=0.60

P<0.05）

reexperience（r=0.53

P<0.05）

avoidance/numbness（r=0.54

P<0.05）

increased awareness（r=0.59

P <0.05）. Conclusions The first-line medical staffs against COVID-19 have post-traumatic stress disorder and mental health problems

which were mutually affected. In order to reduce the post-traumatic stress response of the hospital staffs

need to take psychological intervention measure in time.