Objective To understand the current situation of influenza in a college in Beijing and provide a scientific basis for prevention and control of influenza in colleges or universities.Methods A total of 510 cases of fever clinic visits from a university hospital in Beijing from December 2017 to February 2018 were collected.The cases were divided into the positive group and the negative group in accordance with the results of influenza virus antigen detection.The positive group were further classified into influenza A group and influenza B group according to the type of the patient′s virus.The basic conditions of all patients were analyzed

and the clinical symptoms and laboratory test results of the patients in the negative and positive cases were compared

as well as the clinical symptoms of the patients in the influenza A and B groups.Results Of the 510 patients

312 were males and 198 were females.There were 186 cases（36.5%）with positive influenza virus antigen detection and 324 cases（63.5%）with negative virus antigen detection.Of the 186 influenza patients

148（79.6%）were infected with influenza B virus

38（20.4%）were infected with influenza A virus

107（57.5%）were undergraduates

and79（42.5%）were graduate students.The incidence of cough

sore throat

body aches

catarrh and gastrointestinal symptoms in the positive group were 87.1%

95.2%

76.9%

71.0%and 49.5%

respectively

which were higher than those in the negative group（33.3%

17.6%

42.6%

16.4% and 7.4%

respectively）

and the difference was statistically significant（P

<

0.05）.The incidence of cough in the influenza A group were 94.7%

which was significantly higher than 79.1% in the influenza B group（P

<

0.05）.The incidence of body aches and catarrhal symptoms in the influenza A group were 50.0% and 60.5%

respectively

which were significantly lower than 78.4%and 81.1%in the influenza B group（P

<

0.05）.The white blood cell count of patients in the positive case group was（5.61±1.14）×10

9

/L

which was lower than that in the negative case group（7.86±2.14）×10

9

/L

and the difference was statistically significant（P

<

0.05）.Conclusion Medical staff in colleges or universities need to pay more attention to influenza-like cases

so that early detection

early isolation and early treatment of influenza can be done to reduce the incidence of influenza and ensure the health of teachers and students.