Objective To study the factors influencing 5years cumulative survival of patients with acute coronary syndrome（ACS）.Methods 285 patients with ACS from a hospital in Pingdingshan city were selected as research objects

and on admission patients′gender

age

body mass index（BMI）

hypertension history

diabetes mellitus

smoking history

family history of coronary heart disease

cardiac shock were recorded.After being admitted to hospital within 24hpatients′serum in which high-sensitivity c-reactive protein（hsCRP）

fasting blood glucose（FBG）

creatinine（SCr）

triglyceride（TG）

total cholesterol（TC）

low-density lipoprotein cholesterol（LDL-C）

high density lipoprotein cholesterol（HDL-C）levels were detected;after discharge the patient′s survival time were recorded and the influencing factors of the 5years cumulative survival for patients were analyzed.Results By the end of the follow-up the cumulative survival was 70.1%（19cases lost to follow-up and died of other factors

82 cases died of heart vascular disease and 184 cases survived）.Single factor Cox proportional hazards analysis results showed that the factors influencing 5years cumulative survival of patients included age

history of diabetes

smoking history

family history of coronary heart disease

complication of left ventricular dysfunction（LVF）

complication of cardiac shock

complication of ventricular fibrillation

hs-CRP≥10.0mg/L

SCr≥120μmol/L（P

<

0.05）;Multiariable Cox proportional hazards analysis results showed that the influence factors of 5years cumulative survivalwere age

the hsCRP≥10.0mg/L

SCr≥120μmol/L（P

<

0.05）.Comparing the 5years cumulative survival of patients whose hs-CRP

<

10.0mg/L and hs-CRP≥10.0mg/L

the difference was statistically significant（χ

2

=14.076

P

<

0.01）;in the comparsion between that of patients whose SCr

<

120μmol/L and SCr≥120μmol/L

the difference was statistically significant（χ

2

=11.548

P

<

0.01）;in the comparison between patients aged 61 to 70with patients aged 70 and older

the difference was statistically significant（χ

2

=7.602

19.842;P

<

0.01）.Conclusion hs-CRP

SCr levels and age are the main factors influencing the cumulative survival（5years）of patients with ACS and effective measures could be taken to monitor and control the levels of hs-CRP

SCr which is meaningful for improving the prognosis of patients and reduce mortality.