Objective To assess the clinical efficacy of low-dose metronidazole combined with lactic acid bacteria in treating gestational trichomonas vaginitis.Methods A total of 140 women diagnosed with gestational trichomonas vaginitis were recruited from a Shenyang hospital during Sep.2014 to Mar.2016.Patients were randomized into the trial group（n=75

low-dose metronidazole+lactic acid bacteria vaginal capsule）and the control group（n=65

low-dose metronidazole alone）.The total effective rate

the incidence of adverse events

the recurrence rate and the Short Form 36 Health survey Questionnaire（SF-36）score at 6 months were compared between the two groups.Results The total effective rate and the SF-36 score in the trial group were significantly higher compared with the control group（P<0.05）.The incidence of adverse events was similar between the trial group and the control group（1.33% vs.1.54%

P>0.05）.At 6months

no relapse was observed in the trial group

while the recurrence rate was up to 18.46%in the control group（P<0.05）.Conclusion Low-dose metronidazole combined with lactic acid bacteria is very effective in treating gestational trichomonas vaginitis

which may improve the quality of life of patients and deserve more widespread clinical use.