Objective To evaluate the effect of transurethral bipolar plasma resection（TKRP）on the treatment of benign prostatic hyperplasia（BPH）.Methods 101 cases of patients with BPH admitted in The First Hospital of Dandong City were randomly divided into a control group（n=48）and an observation group（n=53）;the control group were treated with suprapubic transvesical prostatectomy（SPP）and the observation group were treated with TKRP;surgery-related indicators

postoperative stress and prognosis indicators were observed in both groups.Results In the observation group

patients′peri-operative bleeding

operation time and postoperative drainage

postoperative bed time were less than the control group and the differences were statistically significant（P<0.05）;the insulin level of the observation group was higher than the control group

the blood glucose level and the numeric rating scale（NRS）scores

Hamilton depression scale（HAMD）scores and Hamilton anxiety scale（HAMA）scores were lower than the control group

and the differences were statistically significant（P<0.05）;International prostate symptom scores（IPSS）were lower than the control group

but Karnofsky performance status scale（KPS）scores and quality of life questionnaire（QLQ-C30）scores were higher than the control group

and the differences were statistically significant（P<0.05）.Conclusion TKRP in treating BPH can effectively reduce patients′postoperative stress response with small surgical trauma and good long-term prognosis

which is worthy of clinical application and promotion.