Objective To investigate the occurrence of Zhuzhou adverse effects following immunization

explore its features and evaluate the safety of vaccination.Methods Through the surveillance system of state adverse effects following immunization（AEFI）

data of adverse effects from 2012 to 2014in Zhouzhou city were collected and analyzed with descriptive epidemiological method.Results From 2012 to 2014

Zhuzhou reported32 cases of adverse effects following immunization and the reporting rate was 0.73/100 000;the reporting rate of severe adverse effects was 0.14/100 000.Adverse effects occurred mainly in one-year-old and under oneyear-old children

accounting for 56.25%

and girls were slightly higher than boys;adverse effects occurred mainly in the third quarter of the year;district-level incidence of adverse effects reported were slightly lower than the county level.The main clinical diagnosis of adverse effects was allergic rash

severe adverse effects were rare

mainly within 24 hours after vaccination

the adverse effects were cured or improved.ConclusionZhuzhou adverse effects following immunization occurs mainly in children aged one year old or under one year old and on many occasions

adverse effects are at a lesser degree

and mostly transient with a good outcome

an the safety of Zhuzhou current vaccination is acceptable.