52Hz小分子团水对大鼠尿液成分的影响及意义

杨博; 王鹏; 许雪青; 王丰; 靳风烁

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52Hz小分子团水对大鼠尿液成分的影响及意义

论著_实验研究 | 更新时间：2021-08-23

- 52Hz小分子团水对大鼠尿液成分的影响及意义
- The Impact and Significance of 52 Hz Small Molecule Water on Components of Urine in Rats
- 保健医学研究与实践 2016年13卷第2期页码：38-42
- 作者机构：
  
  1. 第三军医大学第三附属医院泌尿外科
  2. 第三军医大学野战外科研究所第七研究室
  3. 第三军医大学第三附属医院检验科
- 作者简介：
- 基金信息：
- DOI：
  中图分类号： R692.4
- 纸质出版日期：2016，
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[1]杨博,王鹏,许雪青,王丰,靳风烁.52Hz小分子团水对大鼠尿液成分的影响及意义[J].保健医学研究与实践,2016,13(02):38-42.

Yang Bo, Wang Peng, Xu Xueqing, et al. The Impact and Significance of 52 Hz Small Molecule Water on Components of Urine in Rats[J]. Health Medicine Research and Practice, 2016,13(2):38-42.
[1]杨博,王鹏,许雪青,王丰,靳风烁.52Hz小分子团水对大鼠尿液成分的影响及意义[J].保健医学研究与实践,2016,13(02):38-42. DOI：

Yang Bo, Wang Peng, Xu Xueqing, et al. The Impact and Significance of 52 Hz Small Molecule Water on Components of Urine in Rats[J]. Health Medicine Research and Practice, 2016,13(2):38-42. DOI：

摘要

目的通过乙二醇诱导大鼠肾结石模型观察52Hz小分子团水对尿液成分及尿液过饱和的影响

以探讨其预防结石形成的机制。方法选取60只雌性SD大鼠随机分为4组

即普通水+乙二醇喂养组（A组）、小分子团水+乙二醇喂养组（B组）、普通水喂养组（C组）、小分子团水喂养组（D组）

每组15只。4组大鼠饲养条件相同

均可自由饮水饮食。喂养40d后测定各组大鼠血、尿生化指标

通过尿生化结果计算尿液离子活度积指数

同时观察结石形成情况。结果 A组大鼠24h尿量为（6.70±1.47）mL

均高于B

D组

差异无统计学意义。A组大鼠尿钙水平为（4.31±0.34）mmol/L

均高于B

D组

且差异有统计学意义（P<0.05）。A组大鼠尿草酸水平为（1.24±0.31）mmol/L

均高于B

D组

且差异有统计学意义（P<0.05）。A组大鼠尿柠檬酸水平为（7.76±1.15）mmol/L

B组大鼠尿柠檬酸水平为（8.52±1.34）mmol/L;其中A组与C

D组比较差异有统计学意义（P<0.05）;B组与C

D组比较差异无统计学意义。A组大鼠尿镁浓度最低

为（6.58±0.78）mmol/L

与B

D组比较差异均有统计学意义（P<0.05）;B组大鼠尿镁浓度为（7.52±1.18）mmol/L

与C

D组比较差异有统计学意义（P<0.05）。4组大鼠血钙、血镁、尿素、血磷水平差异无统计学意义。A组大鼠肌酐、尿素氮水平明显高于B

D组

差异有统计学意义（P<0.05）。结论52Hz小分子团可提高尿液中离子溶解度

在降低结石形成离子浓度的同时可增加抑制结石形成离子的浓度

进而抑制结石的形成。

Abstract

Objective To investigate the impact of 52 Hz small molecule water on components of urine and urine over-saturation through glycol-induced kidney stones model of rat so as to explore the mechanism of inhibiting stone formation.Methods 60 female SD rats were randomly divided into four groups

namely

ordinary water+glycol feeding group（Group A）

small molecule water+glycol feeding group（Group B）

ordinary water feeding group（Group C）

small molecule water feeding group（Group D）

15 rats in each group.All rats were under the same rearing condition and they were free to drink and eat.After 40 days

all groups were tested blood and urine biochemical index

their urine ionic activities were calculated with urinary biochemical results and stone formation was observed.Results In Group A

rats′urine volume of 24 hours was（6.70±1.47）mL

higher than Groups B

C and D

but the differences were not statistically significant.Urinary calcium of Group A was（4.31±0.34）mmol/L

higher than Groups B

C and D

and the differences were statistically significant（P<0.05）.Urinary oxalate of Group A was（1.24±0.31）mmol/L

higher than Groups B

C and D

and the differences were statistically significant（P<0.05）.Urinary citrate of Group A was（7.76±1.15）mmol/L and that of Group B was（8.52±1.34）mmol/L;the differences between Group A and Groups C and D were statistically significant（P<0.05）and there were no significant differences between Group B and Groups C and D.Urinary magnesium concentration of Group A was the lowest

（6.58±0.78）mmol/L

and the differences between Group A and Groups B

C and D were statistically significant（P<0.05）;urinary magnesium concentration of Group B was（7.52±1.18）mmol/L

and the differences between Group B and Groups C and D were statistically significant（P<0.05）.There were no significant differences among four groups in serum calcium

serum magnesium

urea

serum phosphorus.The levels of creatinine and urea nitrogen in rats of Group A were higher than Groups B

C and D

and the differences were statistically significant（P<0.05）.Conclusion 52 Hz small molecule water can increase the solubility of ions in urine and it can reduce the concentration of ions promoting stone formation and increase the concentration of ions inhibiting stone formation in order to inhibit the formation of stones.

关键词

小分子团水乙二醇肾结石尿液过饱和大鼠

Keywords

Small molecule waterGlycolKidney stonesUrine over-saturationRats

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