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福建省福州市第一医院心内科
纸质出版日期:2014,
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[1]江朔晨,吴翔.肌钙蛋白I对不稳定型心绞痛患者早期预后判断的价值[J].保健医学研究与实践,2014,11(04):26-27.
JIANG Shuo chen, WU Xiang. Early Prognostic Value of Cardiac Troponin I in Patients with Unstable Angina Pectoris[J]. Health Medicine Research and Practice, 2014,11(4):26-27.
目的评价肌钙蛋白I(cTnI)定量检测对不稳定型心绞痛(UAP)患者早期预后判断的价值。方法对88例UAP患者(观察组)和54例健康人(对照组)分别进行血清cTnI及肌酸激酶同工酶(CK-MB)的检测
并观察UAP患者住院期间的心脏事件发生率。结果观察组cTnI定量测定平均值为(0.34±0.02)ng/mL
对照组平均值为(0.01±0.00)ng/mL
2组比较差异有统计学意义(P<0.05);2组CK-MB水平比较
差异无统计学意义。88例UAP患者中有35例血清cTnI呈阳性(cTnI≥0.1ng/mL)
53例血清cTnI呈阴性(cTnI<0.1ng/mL)。UAP患者cTnI阳性组在住院期间的急性心肌梗死、心脏性死亡、顽固性心绞痛等心脏事件发生率为82.9%
cTnI阴性组为18.9%
二者比较差异有统计学意义(P<0.01)。结论 cTnI是反映心肌细胞损伤的高灵敏、高特异生化指标
cTnI定量测定对判断UAP患者早期预后有较好的价值。
Objective To evaluate the early prognostic value of quantitative detection of cardiac troponin I(cTnI)in patients with unstable angina pectoris(UAP).Method 88 cases of UAP patients in the observation group and 54 cases of healthy people in the control group were tested serum cTnI and creatine kinase(CK-MB)and the incidence of cardiac events in the observation group was observed.Results The average quantitative determination of cTnI was(0.34±0.02)ng/mL in the observation group
that of the control group was(0.01±0.00)ng/mL and the difference between the two groups was statistically significant(P<0.05);the difference of CK-MB levels in the two groups was not statistically significant.Among the 88 cases of UAP patients
35 cases were detected positive for serum cTnI(cTnI≥0.1ng/mL)
53 cases were detected negative for serum cTnI(cTnI<0.1ng/mL).The incidence of acute myocardial infarction
cardiac death and intractable angina during hospitalization was 82.9%in UAP patients with cTnI positive
the incidence for UAP patients with cTnI negative was 18.9%and the difference was statistically significant(P<0.01).Conclusion CTnI is a biochemical index reflecting high sensitivity and specificity of myocardial cell injury and the quantitative determination of cTnI has a good predictive value for early prognosis of UAP patients.
肌钙蛋白I不稳定型心绞痛早期预后
Cardiac troponin IUnstable angina pectorisEarly prognosis
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