Objective To observe the effects of treating intervertebral disk herniation through internal and external injections of ozone

collagenase

and triamcinolone acetonide（TA）.Method To divide 141paitents of intervertebral disk herniation into three groups:Group A contains 69patients to be treated with a combined application of ozone

collagenase

and TA;Group B contains 36patients to be treated by ozone and TA;Group C contains the rest 36patients treated only by TA.Internal and external Intervertebral injections were applied to all the three groups

and examinations were conducted to them all one week

one month

three months

and six months after the operations respectively

and statistical comparisons were made to the efficacies and VAS marks of the three groups at different time periods.Results The treatment efficacies of Group A and Group B increased steadily as time went by

while that of the Group C dropped accordingly.At both the times three months and six months after the operations

the VAS mark of both Group A and Group B were lower than that of Group C and the differences were statistically significant（P<0.05）.Furthermore

the VAS marks of Group A both three months and six months after the operations were lower than that of Group B with statistically significant differences（P<0.05）.Conclusion The combined application of ozone

collagenase

and TA not only is able to effectively alleviate the pains of post-operation patients

but also has an enduring effect

and is an effective treatment for intervertebral disk herniation.