Objective To observe the clinical effect of felodipine and nitren-dipine in the treatment of essential hypertension.Method 158cases of patients with essential hypertension were randomly divided into two groups and patients in each group were given felodipine tablets and nitren-dipine tablets respectively.Changes in blood pressure of patients in the two groups before and after treatment were observed and compared after 6 weeks.Results Total effective rate in the group treated with felodipine was 91.64%and that in the group treated with nitren-dipine was 88.61%

and differences in therapeutic effect between the two groups had no statistical significance（p>0.05）.Adverse reaction in the felodipine group was lower than the nitren-dipine group.Conclusion Felodipine has an ideal effect in treating essential hypertension with mild adverse reaction and there is no difference in therapeutic effect compared with nitren-dipine

so the felodipine is worth clinical promotion.