This paper elaborates the progress of medication on acute cerebral infarction.It emphasizes that the key to treat cerebral infarction is the ultra-early thrombolytic therapy which can save ischemic penumbra as early as possible

that is

the "therapeutic window" within 6h from the attack.At present

the common thrombolytic drug used in our country is urokinase;early treatments include defibringen（the representative drug is batroxobin）

and the sodium ozagrel has a good therapeutic effect and is safe and reliable in the inhibition of platelet aggregation

and fibrinolysin is a new kind of thrombolytic and anticoagulative drug;the treatment of progressive stroke especially emphasizes on anticoagulation and inhibition of thrombus

and defibrase is often used in combination with low molecular heparin in clinical treatment.This paper also probes into the mechanism of various representative drugs.