Objective To discuss the effects of metformin （DMBG） on the metabolic syndrome （MS） in the elderly population.Method Using DMBG to cure the 55 faculty members who were diagnosed with metabolic syndrome.The usage and dosage is 1 000 mg per day

taken 2 to 3 times

orally at the time of 30 min before meal.The treatment period is 24 weeks.The indicators of MS were detected before and after treatment.Besides

43 cases of non-MS were selected randomly and the indications of MS were detected.Results The indicators of BMI

WC

WHR

BP （SBP

DBP）

FBG

BG2h

TC

TG

LDL-C and FFA of MS group were higher than non-MS group before intervention

but the HDL-C was lower.There were significant differences between the two groups（P<0.05 or P<0.01）.The indicators of BMI

WC

WHR

FBG

BG2h

TG

LDL-C and FFA in MS group after DMBG intervention were lower than that before intervention

while the HDL-C was higher.The difference had statistical significance（P<0.05 or P<0.01）.Though the indicators of BP （SBP

DBP）

TC were lower than before

the difference had no statistical significance （P>0.05）.Conclusion DMBG can improve glucose and lipid metabolism and lose weight.It plays a positive role in preventing angiopathy of MS patients among the middle aged and elderly people.