Objective To study the effect of exercise training on the bone mineral contant （BMC） and the bone mineral density （BMD） in ovariectomized rats. Method Female SD rats were divided into 4 groups as follow: normal control （SHAM）

ovariectomized（OVX）

estrogen supplement （OVX+ES）

exercise training （OVX+ET）. The rats of group SHAM had a sham operation

while that of other groups were ovariectomized. 3 months after operation

the rats had been treated for 3 months. The rats of group OVX+ES were given estradiol

and the rats of group D were trained by exercise. The BMD and BMC of tibia and femur were measured. Results The BMD of femur in SHAM group（0.206±0.009） was higher than that of OVX group（0.196±0.012） with significant difference（P<0.05）;The BMC of tibia in OVX+ET group（0.298±0.033） was higher than that of OVX group（0.260±0.033） with significant difference（P<0.05）; The BMD of tibia in OVX group was lower than that of any other three groups with significant difference （P<0.05 or P<0.01）. Exercise training can obviously increase the BMC and BMD of tibia in ovariectomized rats. It is better than hovmonotherapy on increasing the BMD of tibia. Conclusion Exercise training can intervene the formation of postmenopausal osteoporosis.