Objective To observe the therapeutic effect of Shenmai injection on cor-pulmonale complicated by heart failure.Method 54 cas es of cor-pulmonale complicated by heart failure were divided randomly into 2 groups.The control group（27 cases）was treated with bed rest

low salt

content oxygen inhaiorion

keep respiratory tract from impeding

anti-infection

etc;the treatment group（27cases）was treated with Shenmai injection for intravenous drip on the basis of control group therapy method.Results That treating group behaved better than the control group in resisting heart failure

promoted lung role absorption and improved clinical pheumonia of the patients.There is marked diference between the two groups（p<0.01）.Condusion There is better effect and salty of Shenmai injection in treatment of or-pulmonale complicated heart failure.