Lu Rongxin,Zhong Qianjin,Feng Yongjian.Risk factors for congenital heart disease in Chinese population: A meta-analysis[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(12):1265-1268.
Lu Rongxin,Zhong Qianjin,Feng Yongjian.Risk factors for congenital heart disease in Chinese population: A meta-analysis[J].J Amry Med Univ (J Third Mil Med Univ),2011,33(12):1265-1268.DOI:
Objective To study the risk factors for congenital heart disease in Chinese population. Methods A meta-analysis was performed with Stata11.0 for the papers on risk factors for congenital heart disease in Chinese population published in 2000-2010 that were search from PubMed
MEDLINE
Wanfang database
VIP database
and CNKI. Results Twenty case-control papers including 3 076 cases of congenital heart disease and 60 617 controls were searched. Except for passive smoking
the OR of other risk factors was lager than 1. The OR of mental stimulation
common cold in early pregnancy
abnormal child bearing history
exposure to chemical toxic substances
pregnancy complications
alcohol abuse of father
and noise pollution was 3.10
2.92
1.59
2.76
1.93
2.33
and 1.46
respectively
with the exclusion of 95%CI=1. Conclusion Mental stimulation,common cold in early pregnancy,exposure to chemical toxic substances, pregnancy complications
alcohol abuse of father
abnormal child bearing history
and noise pollution are the risk factors for congenital heart disease in Chinese population. However
passive smoking has not been considered a risk factor for congenital heart disease and should be further studied.