WANG Xiang-feng,ZHANG Lian-yang,HE Yu-jun,LI Chun-xue,LIU Bao-hua,TONG Wei-dong.Clinical significance of HSP60 in serum and stool of colorectal cancer patients[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(13):1334-1336.
WANG Xiang-feng,ZHANG Lian-yang,HE Yu-jun,LI Chun-xue,LIU Bao-hua,TONG Wei-dong.Clinical significance of HSP60 in serum and stool of colorectal cancer patients[J].J Amry Med Univ (J Third Mil Med Univ),2007,29(13):1334-1336.DOI:
Objective To evaluate the expressions of human heat shock protein 60 (HSP60) in serum and stool of colorectal cancer patients. Methods HSP60 was detected by indirect ELISA method in serum and stool samples from 20 normal controls and 40 pathologically proved colorectal cancer patients before operation. Results Compared with normal control
HSP60 increased significantly (P0.05) in serum and stool samples of colorectal cancer patients. HSP60 in stool samples of colorectal cancer patients was different in the cases of different types of colorectal cancer(P0.05)
and increased in T
4
and M
4
of colorectal cancer. Conclusion HSP60 is overexpressed in serum and stool samples of colorectal cancer patients.