LI Mengdi, CHEN Yuanwen. Metabolic characteristics of cirrhotic patients and the relationship between nutrients and liver regeneration. [J]. Journal of Southwest Medical University 47(1):10-14(2024)
DOI:
LI Mengdi, CHEN Yuanwen. Metabolic characteristics of cirrhotic patients and the relationship between nutrients and liver regeneration. [J]. Journal of Southwest Medical University 47(1):10-14(2024) DOI: 10.3969/j.issn.2096-3351.2024.01.003.
Metabolic characteristics of cirrhotic patients and the relationship between nutrients and liver regeneration
The disease progression and complications of liver cirrhosis patients are closely related to nutritional status. The incidence rate of malnutrition in liver cirrhosis patients is relatively high,and the prognosis of patients with sarcopenia is even worse. Its metabolic characteristics are the impairment of nutrient intake,absorption and anabolism,and the high metabolic consumption state associated with increased intestinal loss and increased levels of proinflammatory cytokines. Early clinical identification of adverse metabolic states and timely intervention are crucial for the progression of liver cirrhosis in patients. Nutrients,including glucose,amino acids,and fat,may have an impact on the course of liver cirrhosis by influencing the process of liver regeneration,and the related mechanisms are complex and worthy of further research. Whether regulating the regenerative ability of residual normal liver tissue through nutrient supplementation intervention can slow down or even reverse the progression of liver cirrhosis and improve survival rate is an important direction for future basic and clinical research.This article provided a review of the metabolic characteristics of patients with liver cirrhosis and the relationship between nutrients and liver regeneration
aiming to serve as a reference for clinical research.
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Related Institution
Fourth Department of Liver Disease,Beijing Youan Hospital,Capital Medical University
Fourth Department of Liver Disease Center,Beijing YouAn Hospital,Capital Medical University
Department of Infectious Diseases,Nanjing Drum Tower Hospital,The Affiliated Hospital of Nanjing University Medical School
Department of Infectious Diseases,The Third Affiliated Hospital of Sun Yat-Sen University
Guangdong Provincial Key Laboratory of Liver Disease Research