Progress in clinical application of extracorporeal carbon dioxide removal technology

ZHANG Ling; LI Mingpeng

doi:10.3969/j.issn.2096-3351.2023.05.001

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Progress in clinical application of extracorporeal carbon dioxide removal technology

更新时间：2024-02-04

- Progress in clinical application of extracorporeal carbon dioxide removal technology
- Journal of Southwest Medical University Vol. 46, Issue 5, Pages: 369-373(2023)
- 作者机构：
  
  1. 四川大学华西医院肾脏内科,成都,610041
  2. 四川大学华西医院肾脏病研究所,成都,610041
  3. 简阳市人民医院肾内科(简阳,641400
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2096-3351.2023.05.001
  CLC：
- Published：2023，
  
  Published Online：20 September 2023，
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ZHANG Ling, LI Mingpeng. Progress in clinical application of extracorporeal carbon dioxide removal technology. [J]. Journal of Southwest Medical University 46(5):369-373(2023)
DOI：

ZHANG Ling, LI Mingpeng. Progress in clinical application of extracorporeal carbon dioxide removal technology. [J]. Journal of Southwest Medical University 46(5):369-373(2023) DOI： 10.3969/j.issn.2096-3351.2023.05.001.

摘要

体外二氧化碳清除技术（extracorporeal carbon dioxide removal，ECCO2R）旨在去除血液中二氧化碳，以缓解高碳酸血症和相关酸中毒的不良影响，为保护性甚至超保护性机械通气提供条件，有助于减少有创呼吸机使用，缩短呼吸机带机时间。近年来，该技术在急性呼吸窘迫综合征（acute respiratory distress syndrome，ARDS）、慢性阻塞性肺疾病急性加重（acute exacerbation of chronic obstructive pulmonary disease，AECOPD）、新冠肺炎及等待肺移植手术等患者中发挥了重要作用。本文就近年来国内外ECCO2R 的临床应用进展做一述评，以供临床进一步推广提供参考与借鉴。

Abstract

Extracorporeal Carbon dioxide removal (ECCO2R) is designed to remove carbon dioxide from the blood to alleviate the adverse effects of hypercapnia and related acidosis. It provides conditions for protective or even super-protective mechanical ventila⁃ tion

helping to reduce the use of invasive ventilators and shorten the duration of mechanical ventilation. In recent years

the technique has played an important role in acute respiratory distress syndrome(ARDS)

acute exacerbation of chronic obstructive pulmonary disease (AECOPD)

COVID-19 and patients waiting for lung transplantation. This article reviews the progress of clinical application of ECCO2R at home and abroad in recent years

and provide reference for its further clinical application and promotion.

关键词

体外二氧化碳清除高碳酸血症急性呼吸窘迫综合征慢性阻塞性肺疾病肺移植

Keywords

Extracorporeal carbon dioxide removallHypercapniaAcute respiratory distress syndromeChronic obstructive pul⁃ monary diseaseLung transplantation

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