Acute severe hepatitis of unknown aetiology in children and its management

WANG Nengli; WANG Jianshe

doi:10.3969/j.issn.2096-3351.2022.06.003

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Acute severe hepatitis of unknown aetiology in children and its management

更新时间：2023-05-05

- Acute severe hepatitis of unknown aetiology in children and its management
- Journal of Southwest Medical University Vol. 45, Issue 6, Pages: 474-477(2022)
- 作者机构：
  
  复旦大学附属儿科医院感染传染科,上海,200000
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2096-3351.2022.06.003
  CLC：
- Published：2022，
  
  Published Online：20 November 2022，
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WANG Nengli, WANG Jianshe. Acute severe hepatitis of unknown aetiology in children and its management. [J]. Journal of Southwest Medical University 45(6):474-477(2022)
DOI：

WANG Nengli, WANG Jianshe. Acute severe hepatitis of unknown aetiology in children and its management. [J]. Journal of Southwest Medical University 45(6):474-477(2022) DOI： 10.3969/j.issn.2096-3351.2022.06.003.

摘要

自2022年年初，儿童不明原因严重急性肝炎引起关注。截至6月22日，已有33个国家共报告了920例疑似病例，重症占比较高。国内虽尚无相关病例报告，为提前做好诊疗准备，国家卫生健康委办公厅亦发布了《不明原因儿童严重急性肝炎诊疗指南（试行）》。基于现有已公开的资料，本文将从儿科临床医生的角度，初步梳理儿童不明原因严重急性肝炎的定义、可能病因和临床特征，浅谈其评估和治疗策略，以期增强儿科临床医生对该病的认识和处治能力。

Abstract

Since the beginning of 2022，acute severe hepatitis of unknown aetiology in children has attracted great attention. As of June 22，a total of 920 probable cases have been reported from 33 countries with a high proportion of severe cases. To prepare for the management of possible cases，the National Health Commission of the People's Republic of China issued the Guidelines for acute severe hepatitis with unknown aetiology in children （Trial）. Based on the published data，this paper summarized its definition，possible etiology and clinical features from a perspective of pediatrician，and discussed the strategies of evaluation and treatment，in order to enhance the cognition of pediatric clinicians for this disease.

关键词

儿童不明原因严重急性肝炎临床特征诊断治疗

Keywords

Acute severe hepatitis of unknown aetiologyClinical featuresDiagnosisTreatment

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Related Institution

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