Hypertension is a global public health problem. The number of patients is large，but the diagnosis rate，treatment rate and control rate are low and unevenly distributed. The burden of hypertension in developing countries shows a rapid growth trend，which has become one of the main reasons endangering people's health. In order to improve blood pressure control，two important international guidelines for hypertension have been issued one after another，which provides an important reference for the diagnosis，treatment and management of hypertension all over the world. One of the core points of the new guidelines is to emphasize the importance of drug combination in antihypertensive treatment. Optimizing the initial combination and the popularization and application of single pill combination are effective ways to improve the control rate of antihypertensive and improve treatment compliance at present.