Mechanoresponsive biomaterials in regenerative rehabilitation for bone injury

doi:10.3969/j.issn.2096-3351.2021.05.017

您当前的位置：

首页 >

文章列表页 >

Mechanoresponsive biomaterials in regenerative rehabilitation for bone injury

更新时间：2023-04-16

- Mechanoresponsive biomaterials in regenerative rehabilitation for bone injury
- Journal of Southwest Medical University Vol. 44, Issue 5, Pages: 531-537(2021)
- 作者机构：
  
  1. 西南医科大学附属医院康复医学科,泸州,646000
  2. 西南医科大学康复医学系,泸州,646000
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.2096-3351.2021.05.017
  CLC：
- Published：2021，
  
  Published Online：20 September 2021，
扫描看全文
Mechanoresponsive biomaterials in regenerative rehabilitation for bone injury. [J]. Journal of Southwest Medical University 44(5):531-537(2021)
DOI：

Mechanoresponsive biomaterials in regenerative rehabilitation for bone injury. [J]. Journal of Southwest Medical University 44(5):531-537(2021) DOI： 10.3969/j.issn.2096-3351.2021.05.017.

摘要

单独的再生医学和康复疗法还不能完全满足严重骨损伤后的功能恢复需求。再生康复可以促进骨组织的修复和功能重建，以更好地实现损伤骨的恢复。机械刺激可以刺激细胞的生长和分化并促进损伤骨的修复，而骨组织工程是骨再生最有潜力的技术。因此，机械响应生物材料可能是促进再生医学和康复方法之间协同作用的关键。本文回顾了再生医学和康复治疗在骨损伤修复中的方法，以及各自向临床转化的局限性。通过对机械响应生物材料在骨损伤修复中的前期研究进行总结，评估了机械刺激和机械响应材料联合方法对骨再生的作用。机械响应生物材料的使用融合了再生医学和康复领域，为骨修复创造了新的方向。

Abstract

While regenerative medicine and rehabilitation therapy alone cannot fully restore function after se⁃vere bone injury，regenerative rehabilitation can promote the restoration and functional reconstruction of bone tis⁃sue，achieving a better recovery of injured bone. Mechanical stimulation can stimulate the growth and differentiation of cells and promote the restoration of injured bone，and bone tissue engineering is the most promising technique for bone regeneration. Therefore，mechanoresponsive biomaterials may be the key to synergism between regenerative medicine and rehabilitation therapy. This article reviews the methods of regenerative medicine and rehabilitation therapy in bone injury restoration and their respective limitations in clinical transformation，summarizes previous re⁃search on mechanoresponsive biomaterials for bone injury restoration，and evaluates the effects of mechanical stimu⁃lation and mechanoresponsive biomaterials combined for bone regeneration. The use of mechanoresponsive biomate⁃rials combines regenerative medicine and rehabilitation therapy，creating a new direction for bone recovery.

关键词

骨康复再生机械刺激机械响应生物材料

Keywords

BoneRehabilitationRegenerationMechanical stimulationMechanoresponsive biomaterial

references

查看原文

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

An evaluation of rehabilitation-promoting effect of CPM plus aerosol inhalation after knee arthroplasty and analysis of factors influencing the length of hospital stay

Related Author

ZHENG Shuling

ZHANG Jianhua

ZOU Longfei

XUE Hao

WANG Zhi

Related Institution

Department of Bone and Joine,the Affiliated Hospital of Southwest Medical University

⁰