Bacteriophages were respectively found in 1915 and 1917 by Frederick Twort and Félix d’ Hérelle. The bacteriophages are the viruses infecting bacteria and so naturally of potential in anti-bacterium infec⁃tion. Under the austerity situation of antibiotics resistance

human can not have only one weapon in anti-infection. In 2016

14 Departments of China Government

including Ministry of Public Health and Development-reform Minis⁃try

issued“National Containment Plan of Bacteria Antibiotics-resistance”. The enforcement of this plan is only a start of human against bacterial resistance. The combat to bacterial resistance will be long-term battle. Under this situation

phagotherapy attracts again attention of mankind. In present paper

it will be focus on discovering history of bacteriophages

contribution of phages in scientific research

roles of phages in diseases treatment and roles of phages in agriculture

Industry

dietary hygiene and bio-hightech. We hope this review will benefit to the teach

sci⁃entific research and bacteriophage applications in various fields.