Research progress of ultrasonic neuroregulation of potassium channels in the treatment of pain

YING Yujuan; HUANG Yan; ZHENG Yuanyi

doi:10.16245/j.cnki.issn1008-6978.2021.02.024

您当前的位置：

首页 >

文章列表页 >

Research progress of ultrasonic neuroregulation of potassium channels in the treatment of pain

更新时间：2021-10-08

- Research progress of ultrasonic neuroregulation of potassium channels in the treatment of pain
- Journal of Clinical Ultrasound in Medicine Vol. 23, Issue 2, Pages: 145-148(2021)
- 作者机构：
  
  1. 重庆医科大学附属第二医院超声科
  2. 重庆医科大学附属第二医院麻醉科
  3. 上海交通大学附属第六人民医院超声科
- 作者简介：
- 基金信息：
- DOI：10.16245/j.cnki.issn1008-6978.2021.02.024
  CLC： R402;R445.1
- Published：2021，
扫描看全文
[1]应育娟,黄燕,郑元义.超声神经调控钾通道治疗疼痛的研究进展[J].临床超声医学杂志,2021,23(02):145-148.

YING Yujuan, HUANG Yan, ZHENG Yuanyi. Research progress of ultrasonic neuroregulation of potassium channels in the treatment of pain. [J]. Journal of Clinical Ultrasound in Medicine 23(2):145-148(2021)
[1]应育娟,黄燕,郑元义.超声神经调控钾通道治疗疼痛的研究进展[J].临床超声医学杂志,2021,23(02):145-148. DOI： 10.16245/j.cnki.issn1008-6978.2021.02.024.

YING Yujuan, HUANG Yan, ZHENG Yuanyi. Research progress of ultrasonic neuroregulation of potassium channels in the treatment of pain. [J]. Journal of Clinical Ultrasound in Medicine 23(2):145-148(2021) DOI： 10.16245/j.cnki.issn1008-6978.2021.02.024.

摘要

神经性疼痛不仅影响患者的生活质量

甚至威胁生命

临床难以治愈。背根神经节神经元是神经性疼痛发生和维持的主要解剖部位

其钾离子通道与动作电位的放电频率和由此产生的神经元活动有着密不可分的联系;超声波可以作用于体外单独的细胞离子通道

又可以作用于体内局部组织的离子通道

使其开闭。基于超声的神经调控是一种治疗中枢及外周神经性疼痛很有潜力的方法。本文就钾离子通道作为治疗神经性疼痛的超声靶点机制及研究现状进行综述。

Abstract

Neuropathic pain is difficult to treat clinically

which not only affects the patient ’ s quality of life

but even threatens patient’s life.Dorsal root ganglion（DRG） neurons are the main anatomic sites for the occurrence and maintenance of neuropathic pain

and the potassium channels of DRG neurons are closely related to the firing frequency of action potential and the neuronal activities.Ultrasound can act on the ion channels of individual cells in vitro and the ion channels in local tissues in vivo to make them open or close.In this paper

the mechanism and research status of potassium channel as ultrasound target for the treatment of neuropathic pain are reviewed.

关键词

超声钾离子通道神经性疼痛背根神经节

Keywords

UltrasoundPotassium ion channelsNeuropathic painDorsal root ganglion

references

Views

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Effects of ultrasound-guided thermal ablation on prognosis in patients with advanced colon adenocarcinoma and colorectal liver metastasis

Clinical Application of Two-Dimensional Ultrasound Combined with Three-Dimensional Ultrasound in the diagnosis of Cord-like Structures in Gravid Uterus

Application value of diaphragmatic ultrasonography in respiratory function assessment of premature infants

Clinical value of optic nerve sheath diameter by ultrasonic detection in the diagnosis and treatment of patients with acute increased intracranial pressure

Related Author

应育娟

郑元义

黄燕

韩小军

袁理

郭道宁

王赛君

李明星

Related Institution

重庆医科大学超声影像研究所

电子科技大学医学院附属绵阳医院绵阳市中心医院

电子科技大学医学院附属绵阳医院绵阳市中心医院肿瘤科

西南医科大学附属医院超声医学科

江苏省无锡市新吴区新瑞医院

⁰