Evaluation of microcirculation function of segmental hypertrophic myocardium by myocardial contrast echocardiography

LIU Xuebing; DENG Yan; LI Zhaohuan; YIN Lixue; ZHANG Qingfeng; ZHANG Quanbin

doi:10.16245/j.cnki.issn1008-6978.2020.11.012

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Evaluation of microcirculation function of segmental hypertrophic myocardium by myocardial contrast echocardiography

更新时间：2023-10-09

- Evaluation of microcirculation function of segmental hypertrophic myocardium by myocardial contrast echocardiography
- Journal of Clinical Ultrasound in Medicine Vol. 22, Issue 11, Pages: 834-837(2020)
- 作者机构：
  
  1. 山西医科大学第六临床医学院超声科
  2. 四川省医学科学院四川省人民医院超声医学研究所
- 作者简介：
- 基金信息：
- DOI：10.16245/j.cnki.issn1008-6978.2020.11.012
  CLC： R445.1;R544.1
- Published：2020，
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[1]刘学兵,邓燕,李赵欢,尹立雪,张清凤,张全斌.心肌声学造影定量评估节段增厚心肌微循环功能[J].临床超声医学杂志,2020,22(11):834-837.

LIU Xuebing, DENG Yan, LI Zhaohuan, et al. Evaluation of microcirculation function of segmental hypertrophic myocardium by myocardial contrast echocardiography. [J]. Journal of Clinical Ultrasound in Medicine 22(11):834-837(2020)
[1]刘学兵,邓燕,李赵欢,尹立雪,张清凤,张全斌.心肌声学造影定量评估节段增厚心肌微循环功能[J].临床超声医学杂志,2020,22(11):834-837. DOI： 10.16245/j.cnki.issn1008-6978.2020.11.012.

LIU Xuebing, DENG Yan, LI Zhaohuan, et al. Evaluation of microcirculation function of segmental hypertrophic myocardium by myocardial contrast echocardiography. [J]. Journal of Clinical Ultrasound in Medicine 22(11):834-837(2020) DOI： 10.16245/j.cnki.issn1008-6978.2020.11.012.

摘要

目的应用心肌声学造影定量评估节段增厚心肌及相邻心肌微循环灌注功能。方法选取行心肌声学造影检查的胸痛、胸闷患者32例

其中仅室间隔基底段（IVSB）增厚者16例（病例组）

左室壁厚度正常患者16例（对照组）。应用心肌声学造影定量分析两组IVSB及室间隔中段（IVSM）心肌灌注的峰值强度（A）、上升斜率（k）、达峰时间（T）、A*k值及时间-强度曲线特点。比较两组IVSB与IVSM上述各参数比值间的差异。结果病例组IVSB与对照组IVSB及两组IVSM的T、A、k及A*k值比较差异均有统计学意义（均P<0.05）;病例组与对照组IVSM T、A*k值比较差异均有统计学意义（均P<0.05）;两组IVSB与IVSM A、k、T及A*k比值比较差异均有统计学意义（均P<0.05）。病例组IVSB、IVSM时间-强度曲线分离较对照组的更明显。结论心肌声学造影可早期定量评估节段增厚心肌及相邻心肌微循环功能。

Abstract

ObjectiveTo evaluate the microcirculatory perfusion function of the thickened and adjacent myocardiumby quantitative analysis of myocardial contrast echocardiography（MCE）.MethodsA total of 32 patients with chest pain andchest distress were selected

there were 16 patients with thickened interventricular septum basal segment（IVSB）as case group

and 16 patients with normal left ventricular wall as control group. The peak intensity（A）

ascending slope（k）

peak time（T）

A*k and time-intensity curve of myocardial perfusion in IVSB and the interventricular septum middle segments（IVSM）betweentwo groups were analyzed and compared by quantitative analysis of MCE. The differences in the ratios of the parameters of IVSBand IVSM between the two groups were compared.ResultsThe T

k and A*k of IVSB in case group were statisticallysignificant compared with those of IVSB in control group and IVSM in two groups（all P<0.05）. There were statisticallysignificant differences in T and A*k of the IVSM between the case group and the control group（all P<0.05）

there werestatistically significant differences in the ratios of A

T and A*k of IVSB and IVSM between the case group and thecontrol group（all P<0.05）

and the time-intensity curve separation of case group was more distinct than that of IVSB andIVSM in control group.ConclusionMCE can early assess the segmental hypertrophic myocardium and adjacent myocardialmicrocirculation function quantitatively.

关键词

超声心动描记术心肌声学造影心肌微循环心肌肥厚时间-强度曲线

Keywords

EchocardiographyMyocardial contrast echocardiographyMyocardial microcirculationMyocardial hypertrophyTime-intensity curve

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