Evaluation of liver steatosis and fibrosis in patients with type 2 diabetic nephropathy and their correlation by FibroTouch technique

LIU Lu; SU Benli; ZHANG Yuhong

doi:10.16245/j.cnki.issn1008-6978.2020.10.018

您当前的位置：

首页 >

文章列表页 >

Evaluation of liver steatosis and fibrosis in patients with type 2 diabetic nephropathy and their correlation by FibroTouch technique

更新时间：2023-10-09

- Evaluation of liver steatosis and fibrosis in patients with type 2 diabetic nephropathy and their correlation by FibroTouch technique
- Journal of Clinical Ultrasound in Medicine Vol. 22, Issue 10, Pages: 781-784(2020)
- 作者机构：
  
  1. 大连医科大学附属第二医院超声科
  2. 大连医科大学附属第二医院内分泌科
- 作者简介：
- 基金信息：
- DOI：10.16245/j.cnki.issn1008-6978.2020.10.018
  CLC： R445.1;R587.2;R692.9
- Published：2020，
扫描看全文
[1]刘璐,苏本利,张宇虹.肝脏瞬时弹性成像评价糖尿病肾病患者肝脏脂肪变性和纤维化程度及其相关性分析[J].临床超声医学杂志,2020,22(10):781-784.

LIU Lu, SU Benli, ZHANG Yuhong. Evaluation of liver steatosis and fibrosis in patients with type 2 diabetic nephropathy and their correlation by FibroTouch technique. [J]. Journal of Clinical Ultrasound in Medicine 22(10):781-784(2020)
[1]刘璐,苏本利,张宇虹.肝脏瞬时弹性成像评价糖尿病肾病患者肝脏脂肪变性和纤维化程度及其相关性分析[J].临床超声医学杂志,2020,22(10):781-784. DOI： 10.16245/j.cnki.issn1008-6978.2020.10.018.

LIU Lu, SU Benli, ZHANG Yuhong. Evaluation of liver steatosis and fibrosis in patients with type 2 diabetic nephropathy and their correlation by FibroTouch technique. [J]. Journal of Clinical Ultrasound in Medicine 22(10):781-784(2020) DOI： 10.16245/j.cnki.issn1008-6978.2020.10.018.

摘要

目的探讨肝脏瞬时弹性成像技术FibroTouch评价2型糖尿病肾病（DN）患者肝脏脂肪变性和肝脏纤维化程度的临床价值

分析二者的相关性。方法选取DN患者90例

根据肾小球滤过率（eGFR）将其分为3组:eGFR≥90 ml·min

-1

·1.73 m

-2

者为A组（30例）

60 ml·min

-1

·1.73 m

-2

≤eGFR

90 ml·min

-1

·1.73 m

-2

者为B组（30例）

eGFR

60 ml·min

-1

·1.73 m

-2

者为C组（30例）

同时选取30名健康志愿者为对照组。应用FibroTouch技术获得并比较各组肝脏脂肪衰减值和肝脏硬度值

分析两者相关性。结果各组肝脏脂肪衰减值和肝脏硬度值比较

A、B、C组均明显高于对照组

B、C组均高于A组

C组高于B组

差异均有统计学意义（均P

0.05）。相关性分析显示

肝脏脂肪衰减值与肝脏硬度值呈正相关（r=0.733

0.01）。结论应用FibroTouch技术可以准确、无创地评价DN患者的肝脏脂肪变性和纤维化程度

具有重要的临床意义。

Abstract

Objective To evaluate the degree of liver fibrosis and steatosis

and their correlation in patients with type 2 diabetic nephropathy（DN）by Fibro Touch technique.Methods Ninety patients with type 2 diabetic nephropathy were enrolled and divided into three groups according to the level of estimate glomerular filtration rate（eGFR）:eGFR≥90 ml·min

-1

·1.73 m

-2

as group A（n=30）

60 ml·min

-1

·1.73 m

-2

≤ eGFR

90 ml·min

-1

·1.73 m

-2

as group B（n=30）and eGFR

60 ml·min

-1

·1.73 m

-2

as group C（n=30）. Meanwhile

30 healthy volunteers were enrolled as control group. The fat attenuation value and the liver stiffness value of above groups were obtained by Fibro Touch technique

and the correlation was analyzed.Results The fat attenuation values and the liver stiffness values of group A

B and C were significantly higher than that of control group（all P

0.05）.The fat attenuation values and the liver stiffness values of group B and C were higher than those of group A（P

0.05）

and group C were higher than those of group B（all P

0.05）. The fat attenuation value was positively correlated with the liver stiffness value（r=0.733

0.01）.Conclusion The degree of liver steatosis and fibrosis of DN patients can be evaluated accurately and non-invasively by Fibro Touch technique with an important clinical value.

关键词

超声检查瞬时弹性成像脂肪肝肝纤维化糖尿病肾病

Keywords

UltrasonographyFibroTouchFatty liverHepatic fibrosisDiabetic nephropathy

references

Views

114

下载量

CSCD

Alert me when the article has been cited

提交

Tools

Publicity Resources

Evaluation of liver steatosis and fibrosis in patients with Type 2 diabetic nephropathy and their correlation by FibroTouch technique

Differential diagnostic value of ultrasound radiomics in parathyroid adenoma and parathyroid hyperplasia

Ultrasonic differential diagnosis of appendicitis and normal appendix within critical outer diameter

Related Author

刘璐

张宇虹

苏本利

马可欣

杨雨薇

吕发金

刘丽萍

冯钰瑾

Related Institution

The Second Hospital of Dalian Medical University

Department of Ultrasound，the First Affiliated Hospital of Chongqing Medical University

重庆医科大学附属第一医院放射科

The Second Hospital of Hebei Medical University

Department of Ultrasound,Hangzhou Xixi Hospital,Affiliated to Zhejiang University Medical CollegeHangzhou

⁰