Objective To investigate the application value of real-time three-dimensional echocardiography（RT-3 DE）combined with two-dimensional speckle tracking imaging（2 D-STI）in the evaluation of left atrial function in patients withessential hypertension（EH）.Methods According to the index of the left atrium diameter

86 patients with EH were dividedinto the non-left atrial enlargement（NLAE）group of 43 cases and the left atrial enlargement（LAE）group of 43 cases.70 healthysubjects who were examined in the same period as the control group.The changes of the left atrial maximum volume（LAVmax）

left atrial minimum volume（LAVmin）

left atrial stroke volume（LASV）

global ejection fraction（LAEF）

active ejection fraction（LAAEF）

passive ejection fraction（LAPEF）and left atrial pre systolic volume（LAVpre）were measured by RT-3 DE.The peakstrain rate of different left atrial walls

the mean value of early and late diastolic peak strain rate（mSRs

mSRe

mSRa）weremeasured by 2 D-STI.The correlation between the parameters of left atrial volume and left atrial strain rate was analyzed.Results The RT-3 DE parameters of the LAE group were significantly different from those of the NLAE group and thenormal control group（all P<0.05）

and the differences of LAAEF

LAPEF and LAVpre between NLAE group and the normalcontrol group were statistically significant（all P<0.05）.The 2 D-STI parameters of the LAE group were statistically different from those of the NLAE group and the normal control group（all P<0.05）.The differences between the NLAE group and thenormal control group were statistically significant（all P<0.05）.Correlation analysis showed that mSRs and LAEF

mSRe andLAPEF

mSRa and LAAEF in EH patients were positively correlated（r=0.694

0.807

0.837

P=0.000

0.002

0.000）.Conclusion RT-3 DE combined with 2 D-STI can not only accurately detect the left atrial remodeling in EH patients

but alsoassess the myocardial function.It has good clinical application value in early detection of impaired atrial myocardial function inpatients with EH.