Objective To investigate the diagnostic value of gastrointestinal contrast-enhanced ultrasonography and acoustic pulse radiation force imaging（ARFI） in benign and malignant lesions of gastric wall.Methods A total of 67 patients with thickened gastric wall were retrospectively analyzed.They were divided into benign group（49 cases） and malignant group（18 cases） according to the results of pathological biopsy.Both groups of patients underwent gastrointestinal contrast-enhanced ultrasonography and ARFI

gastric emptying half-time(t

1/2

)

gastric antrum motility index（MI） and shear wave velocity（SWV）were recorded.ROC curve were drawn to compare the diagnostic efficacy of the above indicators in common malignant lesions of gastric wall.Results The t

1/2

and SWV of benign group were（73.04±18.65） min and（1.38±0.26）m/s

respectively

which were lower than those of malignant group[（84.20±21.44） min and（2.41±0.74）m/s].The MI was 63.37±21.05 in benign group

which was higher than that of malignant group（52.22±16.55）

and the difference were statistically significant（all P

<

0.05）.ROC curve analysis showed that the cutoff values of t

1/2

MI and SWV were 100.625 min

62.42 and 1.66 m/s

respectively

the sensitivity were 38.9%

50.0% and 87.9%

the specificity were 100%

51.0% and 81.8%

respectively

the areas under the curve were0.671

0.260 and 0.935

respectively.Conclusion The value of ARFI in the diagnosis of common benign and malignant lesions of gastric wall is superior to that of gastrointestinal contrast-enhanced ultrasonography.