ObjectiveTo explore the application value of transvaginal real time shear wave elastography（SWE）in the diagnosis of benign and malignant cervical diseases.MethodsForty-nine cervical carcinoma patients diagnosed by pathological results were employed as cervical carcinoma group

53 cervical intraepithelial neoplasia（CIN）patients and 60 benign cervical lesions patients were respectively employed as CIN group and benign group

and 60 healthy women as control group.Maximum elasticity value and mean elasticity value of the four groups were measured by SWE and compare.ROC curve was drawn to assess the efficacy of elasticity modulus in diagnosis of cervical carcinoma.Results In the control group

there was no statistical difference of mean elasticity value and maximum elasticity value respectively in different physiological periods and mode.Maximum elasticity value and mean elasticity value in the cervical carcinoma group were respectively higher than those in the CIN group

benign group and control group（Bonferroni adjust P<0.017）.There was significant positive correlation between maximum elasticity value or mean elasticity and the degree of cervical lesions（ρ=0.586

0.713

both P=0.000）.Cut-off value of maximum elasticityvalueandmeanelasticityvaluewere 48.08 kPaand36.89 kPa

area under ROC curve were 0.908 and 0.996

respectively.ConclusionMaximum elasticity value and mean elasticity value obtained by SWE can bring satisfying diagnostic efficiency in diagnosis of cervical cancer and precancerous lesions

both are independent to patients’ menstrual cycles and ultrasonic sections.Mean elasticity value can be the significant observed indicator in the diagnosis of benign and malignant cervical diseases.