Objective To explore the application value of contrast-enhanced ultrasound（CEUS）and shear waveelastography（SWE）in evaluating liver fibrosis for chronic hepatitis B（CHB）patients.MethodsA total of 120 CHB patientsunderwent liver needle biopsy were enrolled in this study.According to biopsy results

they were divided into non-fibrosisgroup（S0 stage

18 cases）

liver fibrosis group（S1～S3 stage

73 cases）and cirrhosis group（S4 stage

29 cases）.The hepaticarteriovenous transit time（HAVTT1 and HAVTT2）and liver elasticity measurement value in each group were obtained by CEUSand SWE.ResultsWith the degree of liver fibrosis increasing

HAVTT1 and HAVTT2 were gradually shortened

and liverelasticity measurement value was gradually increased. There were significant differences in HAVTT1

HAVTT2 and liverelasticity between the non-fibrosis group

fibrosis group and cirrhosis group（all P<0.05）.ROC curve analysis showed that areasunder the curve（AUC）of HAVTT1 and HAVTT2 in diagnosis of liver fibrosis and cirrhosis were 0.870

0.851 and 0.889

0.856

respectively.The areas under the curve for liver fibrosis and liver cirrhosis measured by liver elasticity values were 0.953 and0.898

respectively.The diagnostic efficiency of liver elasticity measurement value was significantly better than that of HAVTT1 and HAVTT2（both P<0.05）.ConclusionThe liver elasticity value obtained by SWE is superior to CEUS in the diagnosis of liverfibrosis and cirrhosis in patients with CHB.