Research progress of nano drug delivery system based on ultrasoundtargeted microbubble destruction technology

ZHOU Houren; ZHANG Yue; XIN Ying; LI Shihui; LIU Xiaoqi; LIU Zhijun

doi:10.16245/j.cnki.issn1008-6978.2020.03.018

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Research progress of nano drug delivery system based on ultrasoundtargeted microbubble destruction technology

更新时间：2021-10-08

- Research progress of nano drug delivery system based on ultrasoundtargeted microbubble destruction technology
- Journal of Clinical Ultrasound in Medicine Vol. 22, Issue 3, Pages: 208-211(2020)
- 作者机构：
  
  中国医科大学附属盛京医院超声科
- 作者简介：
- 基金信息：
- DOI：10.16245/j.cnki.issn1008-6978.2020.03.018
  CLC： R943
- Published：2020，
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[1]周厚妊,张月,辛莹,李诗慧,刘小奇,刘治军.基于超声靶向微泡破坏技术的纳米给药系统的研究进展[J].临床超声医学杂志,2020,22(03):208-211.

ZHOU Houren, ZHANG Yue, XIN Ying, et al. Research progress of nano drug delivery system based on ultrasoundtargeted microbubble destruction technology. [J]. Journal of Clinical Ultrasound in Medicine 22(3):208-211(2020)
[1]周厚妊,张月,辛莹,李诗慧,刘小奇,刘治军.基于超声靶向微泡破坏技术的纳米给药系统的研究进展[J].临床超声医学杂志,2020,22(03):208-211. DOI： 10.16245/j.cnki.issn1008-6978.2020.03.018.

ZHOU Houren, ZHANG Yue, XIN Ying, et al. Research progress of nano drug delivery system based on ultrasoundtargeted microbubble destruction technology. [J]. Journal of Clinical Ultrasound in Medicine 22(3):208-211(2020) DOI： 10.16245/j.cnki.issn1008-6978.2020.03.018.

摘要

纳米给药系统是治疗多种疾病

尤其是肿瘤的一种极具应用潜力的方法。然而

目前其药物输送效率仍难以满足靶向治疗的需要。超声靶向微泡破坏（UTMD）技术作为一种安全的物理靶向方法

可以增强组织渗透性和细胞膜通透性

进而提高纳米给药系统的药物递送效率。本文就UTMD介导的纳米给药系统的研究进行综述。

Abstract

Nano-drug delivery system is a potential method to treat many diseases

especially tumors.However

drug delivery efficiency does not meet the needs of targeted therapy.Ultrasonic-targeted microbubble destruction（UTMD）

as a safe physical targeting method

can enhance tissue and cell membrance permeability

improving the drug delivery efficiency of nanodrug delivery system.This article reviews the research of UTMD-mediated nano drug delivery systems.

关键词

超声靶向微泡破坏技术靶向性纳米给药系统肿瘤

Keywords

Ultrasound-targeted microbubble destruction technologyTargetedNano-drug delivery systemTumor

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李攀

林晓红

曾红春

杨文艳

刘治军

刘小奇

李诗慧

辛莹

Related Institution

重庆医科大学附属第二医院超声科，超声分子影像重庆市重点实验室

Department of Ultrasound,the First Affiliated Hospital of Xinjiang Medical University

新疆医科大学第一附属医院超声诊断科

Shengjing Hospital of China Medical University

北京大学肿瘤医院

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