The dynamical analysis of the effect of sodium thiosulfate on the biotrans-formation of cyanide to thiocyanate in rats and in isolated perfused rat liver showed that the rate of "spontaneous" biotransformation of cyanide was rather slow
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第三军医大学病理生理学教研室
the maximun of effectiveness being nearly reached , when the molar ratio between thiosulfate and cyanide was 3:1. However thiosulfate could hardly increase the total amount of cyanide converted. It was suggested that the contribution of thiosulfate as an